Osteolysis is a pathological process accompanied by bone resorption, in which the bone tissue disappears completely and without a trace, in the absence of reactive changes from the surrounding soft tissues and the rest of the bone. The osteolytic form of RA (rheumatoid arthritis) cannot be attributed to true osteolysis of bone tissue. This form of RA (rheumatoid arthritis) appears to be a manifestation of destructive arthritis. However, the destruction of the bones in this case is so significant that the epiphyses of the bones are almost completely destroyed, while they are significantly reduced in size and deformed.
With true osteolysis of short tubular bones, not only the epiphyses, but also the metaphyses and diaphyses of the bones undergo resorption, in some cases the bone can completely lyse, which never happens with RA (rheumatoid arthritis). One of the options for osteolysis is acroosteolysis of the nail tuberosities of the distal phalanges of the fingers. True osteolysis is an extremely characteristic radiological symptom of psoriatic arthropathy and SJS (systemic scleroderma).